Lacunar amnesia is the loss of memory about one specific event. It is a type of amnesia that leaves a lacuna (a gap) in the record of memory.
According to Steven Johnson, (the author of Mind Wide Open: Your Brain and the Neuroscience of Everyday Life):
"Scientists believe memories are captured and stored by two separate parts of the brain, the hippocampus, the normal seat of memory, and the amygdala, one of the brain's emotional centers. People who, due to hippocampus damage, are incapable of forming long-term memories can still form subconscious memories of traumatic events if their amygdala is intact. Someone suffering from the Memento condition would likely have a feeling of general unease encountering a person who had harmed them in the past, though they wouldn't be able to put their finger on why. As the plot of Eternal Sunshine correctly suggests, the brain is designed to preserve emotionally strong memories. Even amnesiacs, under the right circumstances, can remember their past feelings."
Furthermore, according to Alex Chadwick speaking on NPR:
"Some scientists now believe that memories effectively get rewritten every time they're activated. Studies on rats suggest that if you block a crucial chemical process during the execution of a learned behavior - pushing a lever to get food, for instance - the learned behavior disappears. The rat stops remembering. Theoretically, if you could block that chemical reaction in a human brain while triggering a specific memory, you could make a targeted erasure. Think of a dreadful fight with your girlfriend while blocking that chemical reaction, and zap! The memory's gone."
Daniel Goleman, in his book Vital Lies, Simple Truths, defines a lacuna as :
"... lacuna, from the Latin for gap or hole, to refer to the sort of mental apparatus that diversionary schemas represent. A lacuna is, then, the attentional mechanism that creates a defensive gap in awareness. Lacunas, in short, create blind spots
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This type of amnesia is used as a plot element in the movie Eternal Sunshine of the Spotless Mind, in which a company (appropriately named Lacuna) offers the service of having a specific person erased from someone's memories by removing all memories of them.
Similarly, in the manga Fruits Basket, the character Hatori Sohma has the ability to erase a persons memories. This ability is used by the head of the family, Akito, who instructed Hatori to use it when people outside the family discovered their secret. He also had to use the ability to make his fiance, Kana, forget about him because he'd caused her too much pain.
In the movie Heroes The protagonist Jack Dunne (Henry Winkler) learns a horrible truth about a friend of his about which he had known, but has forgotten.
In the BBC series Doctor Who, the character Donna Noble experiences amnesia of this sort when her memories are altered to remove any trace of the Doctor, aliens, or any sort of unearthly strangeness to prevent her mind from burning itself up.